8. Great Dane
The cute, cowardly dog from Mystery Inc., Scooby Doo, comes to mind when we think about Great Danes. Although the dog may be endearing in real life, it would be a good idea to avoid getting on his bad side. The Great Dane is undoubtedly one of the most deadly canine breeds in the world—if not properly cared for, that is—despite the fact that its name and stature give it the appearance of being magnificent.